How often should you get a blood test? Most physicians recommend once a year around the same time as your yearly physical, but this is the bare minimum. If you have any additional health concerns or complicating factors you may be asked to get blood test and urine test more frequently than just once a year. These may include unusual or persistent problems (weight gain or loss), wanting to improve or optimize your health and lastly to reduce your risk of disease or complications. Regular blood tests can catch the warning signs of almost any disease early. Many heart, lung, and kidney conditions can be diagnosed using blood tests.